Severe acute pancreatitis as a complication of COVID-19; a case report
Abstract
COVID-19 is a systemic infectious disease that primarily affects the respiratory system, however, the involvement of extra-pulmonary systems have also been reported. We report a 25-year-old female patient visited the emergency department with a four-day history of severe burning epigastric pain associated with vomiting. The patient was diagnosed as severe acute pancreatitis with concomitant critical COVID-19 based on clinical, biochemical, and imaging findings. The patient was managed with antibiotics, anticoagulation and ventilatory support. Despite aggressive treatment efforts, the patient sustained cardiac arrest in the setting of refractory hypoxemia and passed away on day three of her hospital admission.
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15. Pandanaboyana S, Moir J, Leeds JS, Oppong K, Kanwar A, Marzouk A, et al. SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study. Gut. 2021;70(6):1061-9.
16. Bulthuis MC, Boxhoorn L, Beudel M, Elbers PW, Kop MP, van Wanrooij RL, et al. Acute pancreatitis in COVID-19 patients: true risk? Scand J Gastroenterol. 2021;56(5):585-7.
17. de Sá TC, Soares C, Rocha M. Acute pancreatitis and COVID-19: A literature review. World J Gastrointest Surg. 2021;13(6):574–84.
2. Rodríguez BO, Sánchez TL. The Psychosocial Impact of COVID-19 on health care workers. International braz j urol. 2020;46:195-200.
3. Wang F, Wang H, Fan J, Zhang Y, Wang H, Zhao Q. Pancreatic injury patterns in patients with coronavirus disease 19 pneumonia. Gastroenterology. 2020;159(1):367-70.
4. Jabbari A, Alijanpour E, Maleh PA, Heidari B. Lung protection strategy as an effective treatment in acute respiratory distress syndrome. Caspian J Intern Med. 2013;4(1):560–3.
5. Weston S, Frieman MB. COVID-19: knowns, unknowns, and questions. mSphere. 2020;5(2):e00203-20.
6. Aloysius MM, Thatti A, Gupta A, Sharma N, Bansal P, Goyal H. COVID-19 presenting as acute pancreatitis. Pancreatology. 2020;20(5):1026-7.
7. Kataria S, Sharif A, Rehman AU, Ahmed Z, Hanan A. COVID-19 induced acute pancreatitis: a case report and literature review. Cureus. 2020;12(7):e9169.
8. Mazrouei SSA, Saeed GA, Al Helali AA. COVID-19- associated acute pancreatitis: a rare cause of acute abdomen. Radiol Case Rep. 2020;15(9):1601-3.
9. Liu F, Long X, Zhang B, Zhang W, Chen X, Zhang Z. ACE2 expression in pancreas may cause pancreatic damage after SARS-CoV-2 infection. Clin Gastroenterol Hepatol. 2020;18(9):2128–30.e2.
10. Gonzalo- Voltas A, Fernández- Pérez- Torres CU, Baena- Díez JM. Acute pancreatitis in a patient with COVID-19 infection. Med Clin. 2020;155(4):183–4.
11. Steenblock C, Richter S, Berger I, Barovic M, Schmid J, Schubert U, et al. Viral infiltration of pancreatic islets in patients with COVID-19. Nat Commun. 2021;12(1):3534.
12. Hadi A, Werge M, Kristiansen KT, Pedersen UG, Karstensen JG, Novovic S, et al. Coronavirus disease-19 (COVID-19) associated with severe acute pancreatitis: case report on three family members. Pancreatology. 2020;20(4):665-7.
13. de-Madaria E, Capurso G. COVID-19 and acute pancreatitis: examining the causality. Nat Rev Gastroenterol Hepatol. 2021;18(1):3-4.
14. Patel KP, Patel PA, Vunnam RR, Hewlett AT, Jain R, Jing R, et al. Gastrointestinal, hepatobiliary, and pancreatic manifestations of COVID-19. J Clin Virol. 2020;128:104386.
15. Pandanaboyana S, Moir J, Leeds JS, Oppong K, Kanwar A, Marzouk A, et al. SARS-CoV-2 infection in acute pancreatitis increases disease severity and 30-day mortality: COVID PAN collaborative study. Gut. 2021;70(6):1061-9.
16. Bulthuis MC, Boxhoorn L, Beudel M, Elbers PW, Kop MP, van Wanrooij RL, et al. Acute pancreatitis in COVID-19 patients: true risk? Scand J Gastroenterol. 2021;56(5):585-7.
17. de Sá TC, Soares C, Rocha M. Acute pancreatitis and COVID-19: A literature review. World J Gastrointest Surg. 2021;13(6):574–84.
| Files | ||
| Issue | Vol 6 No 2 (2022): Spring (April) | |
| Section | Case (report / study) | |
| DOI | 10.18502/fem.v6i2.8720 | |
| Keywords | ||
| Case Reports COVID-19 Pancreatitis SARS-CoV-2 | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Muluberhan N, Abdi S, Alemayehu A, Getachew M. Severe acute pancreatitis as a complication of COVID-19; a case report. Front Emerg Med. 2021;6(2):e25.
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