Demographic information and risk factors of stroke patients younger than 65 years old


Objective: The main objective of this study is to evaluate the prevalence of risk factors for and demographics of
patients younger than 65 years old with stroke. Methods: This retrospective cross-sectional study took into consideration all patients younger than 65 years old who were admitted to the emergency department from 2016 to 2018. Some significant criteria such as age, sex, type of stroke, stroke risk factors, and modified Ranking Scale (mRS) were extracted from patients’ medical records. Based on their age, these patients were divided into three groups: younger than 35 years old (Group A), between 35-50 years old (Group B), and older than 50 years old (Group C). Data analysis was carried out using IBM® SPSS® Statistics 20.0 software. Results: A total of 392 patients with stroke were included in this study. Groups A, B, and C included 31, 124, and 237 patients, respectively. Among them, 313 patients (79.84%) were admitted to the hospital in cold seasons, while 73 patients (18.6%) had no symptoms related to stroke at the time of admission. The most common adjustable risk factor among the patients was hypertension (HTN) with a frequency of 230 (58.7%). Of note, the frequency of HTN, diabetes, atrial fibrillation (AF), oral contraceptive pill (OCP) consumption, and coronary artery disease (CAD) in patients was significantly different among these three groups. Conclusion: According to the findings of the present study, the prevalence rate of stroke probably varies for male and female (gender) in the studied groups, which is significantly correlated with age. Among the adjustable risk factors for stroke, HTN, diabetes, AF, OCP consumption, and CAD are significantly correlated with the age.

1. Virani SS, Alonso A, Benjamin EJ, Bittencourt MS, Callaway CW, Carson AP, et al. Heart disease and stroke statistics—2020 update: a report from the American Heart Association. Circulation. 2020;141(9):e139-596.
2. Djalalinia S, Saeedi Moghaddam S, Rezaei N, Rezaei N, Mansouri A, Abdolhamidi E, et al. National and sub-national patterns of mortality from stroke in the Iranian population (1990–2015): Complementary results from the NASBOD study. Int J Stroke. 2020;15(2):132-48.
3. Momeni M, Vahidi E, Seyedhosseini J, Jarchi A, Naderpour Z, Saeedi M. Emergency overcrowding impact on the quality of care of patients presenting with acute stroke. Adv J Emerg Med. 2018;2(1):e3.
4. Hughes M, Lip GY, Guideline Development Group for the NICE National Clinical Guideline for Management of Atrial Fibrillation in Primary and Secondary Care. Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk stratification schema and cost effectiveness data. Thromb Haemost. 2008;99(02):295-304.
5. Aigner A, Grittner U, Rolfs A, Norrving B, Siegerink B, Busch MA. Contribution of established stroke risk factors to the burden of stroke in young adults. Stroke. 2017;48(7):1744-51.
6. Demel SL, Kittner S, Ley SH, McDermott M, Rexrode KM. Stroke risk factors unique to women. Stroke. 2018;49(3):518-23.
7. Roy-O’Reilly M, McCullough LD. Age and sex are critical factors in ischemic stroke pathology. Endocrinology. 2018;159(8):3120-31.
8. Mohindra R, Mishra U, Mathew R, Negi NS. Red Cell Distribution Width (RDW) Index as a Predictor of Severity of Acute Ischemic Stroke: A Correlation Study. Adv J Emerg Med. 2020;4(2):e24.
9. Oshunbade AA, Yimer WK, Valle KA, Clark III D, Kamimura D, White WB, et al. Cigarette smoking and incident stroke in blacks of the jackson heart study. J Am Heart Assoc. 2020;9(12):e014990.
10. Schneider S, Kornejeva A, Vibo R, Kõrv J. Risk factors and etiology of young ischemic stroke patients in Estonia. Stroke Res Treat. 2017;2017:8075697.
IssueVol 6 No 1 (2022): Winter (February) QRcode
SectionOriginal article
DOI 10.18502/fem.v6i1.7676
Adult Demography Risk Factors Stroke

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
Hosseinzadeh N, Ala A, Rahnemayan S, Sadeghi-Hokmabadi E, Gholami Milani A, Rahimpour Asenjan M, Shams Vahdati S. Demographic information and risk factors of stroke patients younger than 65 years old. Front Emerg Med. 2021;6(1):e4.


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