Sample Size Calculation Guide - Part 5: How to calculate the sample size for a superiority clinical trial
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Abstract
In the previous educational articles, we explained how to calculate the sample size for a rate or a single proportion, for an independent cohort study, for an independent case-control study, and for a diagnostic test accuracy study. In this article, we explain how to calculate the sample size for a superiority clinical trial.
1. Fahim NK, Negida A. Sample size calculation guide - part 1: how to calculate the sample size based on the prevalence rate. Adv J Emerg Med. 2018;2(4):e50.
2. Fahim NK, Negida A. Sample size calculation guide - part 2: how to calculate the sample size for an independent cohort study. Adv J Emerg Med. 2019;3(1);e12.
3. Fahim NK, Negida A, Fahim AK. Sample size calculation guide - part 3: how to calculate the sample size for an independent case-control study. Adv J Emerg Med. 2019;3(2):e20.
4. Negida A, Fahim NK, Negida Y. Sample size calculation guide - part 4: how to calculate the sample size for a diagnostic test accuracy study based on sensitivity, specificity, and the area under the roc curve. Adv J Emerg Med. 2019;3(3):e33.
5. Odekerken VJ, van Laar T, Staal MJ, Mosch A, Hoffmann CF, Nijssen PC, et al. Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. Lancet Neurol. 2013;12(1):37-44.
2. Fahim NK, Negida A. Sample size calculation guide - part 2: how to calculate the sample size for an independent cohort study. Adv J Emerg Med. 2019;3(1);e12.
3. Fahim NK, Negida A, Fahim AK. Sample size calculation guide - part 3: how to calculate the sample size for an independent case-control study. Adv J Emerg Med. 2019;3(2):e20.
4. Negida A, Fahim NK, Negida Y. Sample size calculation guide - part 4: how to calculate the sample size for a diagnostic test accuracy study based on sensitivity, specificity, and the area under the roc curve. Adv J Emerg Med. 2019;3(3):e33.
5. Odekerken VJ, van Laar T, Staal MJ, Mosch A, Hoffmann CF, Nijssen PC, et al. Subthalamic nucleus versus globus pallidus bilateral deep brain stimulation for advanced Parkinson's disease (NSTAPS study): a randomised controlled trial. Lancet Neurol. 2013;12(1):37-44.
| Files | ||
| Issue | Vol 3 No 4 (2019): Autumn (October) | |
| Section | Educational Notes in Research Methodology and Medical Statistics | |
| PMCID | PMC6789074 | |
| PMID | 31633104 | |
| Keywords | ||
| Sample Size | ||
| Rights and permissions | |
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
How to Cite
1.
Negida A, Fahim N, Negida Y, Ahmed H. Sample Size Calculation Guide - Part 5: How to calculate the sample size for a superiority clinical trial. Front Emerg Med. 2019;3(4):e49.
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