Massive hemorrhage update: what is known and what we should know?

Abstract

Massive hemorrhage protocol (MHP) is an updated term for the formerly used massive transfusion protocol, highlighting crucial aspects of hemorrhage management other than the transfusion itself. This complex intervention includes acute hemorrhage control; administering tranexamic acid (TXA), preventing hypocalcemia, hypothermia, and acidosis; reversing anticoagulation or correcting coagulopathies; and planning for the next steps in definitive hemorrhage control. Here, we discuss exciting frontiers and challenges of MHP.

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Keywords
Trauma Transfusion Massive Hemorrhage Protocol

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How to Cite
1.
Marcotte A, Bahreini M. Massive hemorrhage update: what is known and what we should know?. Front Emerg Med. 2025;:e18.

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