<?xml version="1.0"?>
<Articles JournalTitle="Frontiers in Emergency Medicine">
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>05</Month>
        <Day>27</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Spontaneous pneumothorax in a pregnant woman with COVID-19: a case report</title>
    <FirstPage>e9</FirstPage>
    <LastPage>e9</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Athar</FirstName>
        <LastName>Rasekhjahromi</LastName>
        <affiliation locale="en_US">Obstetrics and Gynecology Department, Jahrom University of Medical Sciences, Jahrom, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Zahra</FirstName>
        <LastName>Jafarzadehjahromi</LastName>
        <affiliation locale="en_US">Student Research Committee, Jahrom University of Medical Sciences, Jahrom, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Navid</FirstName>
        <LastName>Kalani</LastName>
        <affiliation locale="en_US">Research Center for Social Determinants of Health, Jahrom University of Medical Sciences, Jahrom, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Zahra</FirstName>
        <LastName>Zarei Babaarabi</LastName>
        <affiliation locale="en_US">Women's Health and Diseases Research Center, Jahrom University of medical sciences, Jahrom, Iran.</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>05</Month>
        <Day>02</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>05</Month>
        <Day>09</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Numerous symptoms and complications of COVID-19 include pneumothorax as a rare but potentially-lethal condition. The present case report involved a pregnant woman with COVID-19 presenting with pneumothorax. A 30-year-old pregnant woman with COVID-19 and a gestational age of 32 weeks presented to our hospital with dyspnea, coughs and fever. The rales initially heard in both lungs continued to be heard only in the left lung after 24 hours. Pneumothorax was confirmed through radiology. The emergency cesarean section performed to avoid the potential detrimental effects of the infection on the fetus caused no breathing episodes in the biophysical profile. The patient recovered postpartum without complications and both the mother and the newborn were discharged 12 days later. Spontaneous pneumothorax is a rare complication in COVID-19 pregnant patients that can emerge at any stage of the disease.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/744</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/744/358</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>09</Month>
        <Day>26</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Potential therapeutic approaches in paraquat poisoning: a narrative review</title>
    <FirstPage>e7</FirstPage>
    <LastPage>e7</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Amir</FirstName>
        <LastName>Ghabousian</LastName>
        <affiliation locale="en_US">Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Saeed</FirstName>
        <LastName>Safari</LastName>
        <affiliation locale="en_US">Emergency Medicine Department, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Niloufar</FirstName>
        <LastName>Ansari</LastName>
        <affiliation locale="en_US">Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>12</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>14</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Paraquat dichloride (PQ) poisoning is a relatively rare yet critical medical condition that has a high case fatality rate. Lung tissue is highly susceptible to PQ-induced injury, and respiratory failure is the leading cause of death in these patients. Unfortunately, there is a lack of an effective therapeutic approach to ameliorate outcomes. It is well-known that PQ interferes with a variety of cell signaling pathways and induces the generation of reactive oxygen species (ROS), which ultimately results in cell injury. The traditional treatment decisions have not been able to significantly change the clinical course of PQ poisoning. Moreover, novel therapeutic strategies for PQ poisoning have centered on the inhibition of PQ-induced signaling pathways. In the current review, we sought to provide a bird&#x2019;s-eye view of the available therapeutic approaches in patients with PQ poisoning.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/800</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/800/368</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>10</Month>
        <Day>10</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Basic life support awareness level among medical students in Jordan: a cross-sectional study</title>
    <FirstPage>e1</FirstPage>
    <LastPage>e1</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Ebraheem</FirstName>
        <LastName>Albazee</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad</FirstName>
        <LastName>Alnifise</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Lina</FirstName>
        <LastName>Almahmoud</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Ahmed</FirstName>
        <LastName>Alsaeedi</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammed</FirstName>
        <LastName>Al-balawi</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Talal</FirstName>
        <LastName>Alotaibi</LastName>
        <affiliation locale="en_US">Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
      <Author>
        <FirstName>Aiman</FirstName>
        <LastName>Al Sharei</LastName>
        <affiliation locale="en_US">Department of Basic Medical Sciences, Faculty of Medicine, Hashemite University, Zarqa, Jordan</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>05</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>24</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Objective: Performing basic life support (BLS) in patients with cardiopulmonary arrest decreases mortality and morbidity. In addition, BLS knowledge is a prerequisite for medical graduation. The present study was conducted to determine the awareness level of undergraduate medical students in Jordan regarding BLS and background knowledge.&#xA0;Methods: This cross-sectional study was conducted between 17 April 2021 and 12 May 2021. A validated questionnaire was used as an online Google form and was posted in all medical student groups and Jordanian universities through various social medias. We categorized level of awareness into two groups: adequate awareness for those who got 60% or more, and inadequate awareness for those who got less than 60% in BLS test. Chi-square test was used to compare different variables.&#xA0;Results: A total of 886 students with a mean age of 21.5 (&#xB1; 2.2) years completed the survey, including 552 females (62.3%). Among participated students, only 281 (31.7%) had adequate awareness, whereas 605 (68.3%) had inadequate awareness, with a mean score of 10 (&#xB1; 3.8) out of 20. Surprisingly, there was no statistically significant correlation (P=0.210) between grade point average (GPA) and awareness level among participated students. On the contrary, we detected statistically significant relationships (P&lt;0.001) between various variables and awareness level.&#xA0;Conclusion: Overall, we found that awareness of BLS among medical students in Jordan is not adequate. We can improve the awareness of medical students in this regard through obligating them to educate the general population, especially school students, as a volunteer campaign.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/765</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/765/370</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>11</Month>
        <Day>16</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Simple atrioventricular (AV) dissociation or AV dissociation caused by third degree AV block?</title>
    <FirstPage>e13</FirstPage>
    <LastPage>e13</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Jerry W.</FirstName>
        <LastName>Jones</LastName>
        <affiliation locale="en_US">Chief Instructor, Medicus of Houston, Texas, USA</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>11</Month>
        <Day>15</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>11</Month>
        <Day>15</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">One of the most difficult decisions for many physicians and advanced practice providers occurs when having to distinguish between simple atrioventricular (AV) dissociation and AV dissociation caused by a third degree AV block. Third degree AV block is only one cause of AV dissociation and it is a very infrequent cause. The majority of simple AV dissociations are caused by variations in the balance of sympathetic and parasympathetic inputs from the autonomic nervous system. All of us probably experience an occasional episode of simple AV dissociation while we are asleep. Treatment for simple AV dissociation may be as simple as having the patient get out of bed and walk around the room a few times, while AV dissociation caused by a third degree AV block is going to require an emergent placement of a permanent pacemaker. In order to make this decision properly and confidently, you must have a very clear understanding of the difference. Here, in this educational paper, we aim to discuss more in this regard.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/893</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/893/377</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>09</Month>
        <Day>01</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Professional quality of life and emotional well-being among healthcare workers during the COVID-19 pandemic in Iran</title>
    <FirstPage>e2</FirstPage>
    <LastPage>e2</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Reza</FirstName>
        <LastName>Azizkhani</LastName>
        <affiliation locale="en_US">Department of Emergency Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Farhad</FirstName>
        <LastName>Heydari</LastName>
        <affiliation locale="en_US">Department of Emergency Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Ahmad</FirstName>
        <LastName>Sadeghi</LastName>
        <affiliation locale="en_US">Department of Counseling, Faculty of Education and Psychology, University of Isfahan, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Omid</FirstName>
        <LastName>Ahmadi</LastName>
        <affiliation locale="en_US">Department of Emergency Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Azita</FirstName>
        <LastName>Azimi Meibody</LastName>
        <affiliation locale="en_US">Department of Emergency Medicine, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>06</Month>
        <Day>16</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>23</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Objective:&#xA0;Healthcare workers (HCWs) are among the highest groups impacted by the COVID-19 pandemic. This study aimed to analyze professional quality of life (ProQOL) and its association with emotional well-being in HCWs during the pandemic.&#xA0;Methods:&#xA0;This cross-sectional study was conducted on HCWs being in close contact with COVID-19 patients in Iran. The questionnaires assessing ProQOL, emotional well-being, and demographic and occupational characteristics were recruited via email or social media. The ProQOL was used to measure compassion fatigue (CF), burnout (BO) and compassion satisfaction (CS).&#xA0;Results:&#xA0;Among the respondents, 705 HCWs were enrolled, including a higher proportion of physicians 449 (63.7%), females 452 (64.1%), and married 486 (68.9%). The mean of participants&#x2019; work experience was 8.41 &#xB1; 8.91 years. Almost all of HCWs showed moderate to high levels of CS (98.3%). Also, most of HCWs showed a moderate level of CF (96.3%), and the majority of them (76.6%) had a moderate level of BO. There were significant differences in the duration of contact with COVID-19 patients for all three components of ProQOL and emotional well-being score. Women had a higher level of BO than men (P=0.003). CS was significantly higher in married HCWs than in singles (P=0.007). Pearson correlation coefficient showed that CS had a negative relationship with CF and BO. However, there was a direct correlation between emotional well-being and the CS.&#xA0;Conclusion:&#xA0;During the COVID-19 pandemic, Iranian HCWs showed to have moderate to high levels of CS, and a moderate level of both CF and BO, and showed that emotional well-being had a direct correlation with CS.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/772</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/772/366</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>09</Month>
        <Day>28</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">An interesting case of an atraumatic painful swollen limb in a pregnant woman</title>
    <FirstPage>e10</FirstPage>
    <LastPage>e10</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Debkumar</FirstName>
        <LastName>Chowdhury</LastName>
        <affiliation locale="en_US">Emergency Department, Royal Blackburn Hospital, Blackburn, United Kingdom</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>28</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>08</Month>
        <Day>19</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Phlegmasia cerulea dolens is an uncommon complication of deep venous thrombosis. This is associated with high rates of morbidity if not treated effectively. We present a young lady 13 weeks pregnant with one-day history of left lower limb swelling with pain and discolouration. Bedside ultrasonography revealed thrombosis occluding the common femoral vein and collateral femoral vein. She had history of neonatal alloimmune thrombocytopaenia (NAIT), and had immunotherapy previously. The safest option was to give low molecular weight heparin (LMWH) on an inpatient basis. Anticoagulation with LMWH has been well established as thromboprophylaxis during pregnancy, however, the safety profile of systemic anticoagulation is matter of debate. As highlighted in this scenario the management needs to be tailored on an individual basis. The cause for the extensive deep vein thrombosis could be possibly due to the recent immunoglobulin therapy, undiagnosed prothrombotic state (outwith pregnancy) or the procoagulant state associated with pregnancy.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/820</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/820/369</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>11</Month>
        <Day>01</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">A review on using ultrasound for evaluation of pediatric blunt abdominal trauma</title>
    <FirstPage>e8</FirstPage>
    <LastPage>e8</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Mojtaba</FirstName>
        <LastName>Chardouli</LastName>
        <affiliation locale="en_US">Emergency Medicine Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammadreza</FirstName>
        <LastName>Yasinzadeh</LastName>
        <affiliation locale="en_US">Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad</FirstName>
        <LastName>Meshkini</LastName>
        <affiliation locale="en_US">Emergency Medicine Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Hadi</FirstName>
        <LastName>Jalilvand</LastName>
        <affiliation locale="en_US">International Safe Community Support Center, Research Center for Road Traffic Injury, Tabriz University of Medical Sciences, Tabriz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Hamed</FirstName>
        <LastName>Basir Ghafouri</LastName>
        <affiliation locale="en_US">Emergency Medicine Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Homayoun</FirstName>
        <LastName>Sadeghi-Bazargani</LastName>
        <affiliation locale="en_US">International Safe Community Support Center, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Sayyed Mohammadreza</FirstName>
        <LastName>Mirkarimi</LastName>
        <affiliation locale="en_US">Emergency Medicine Department, Rasool-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2021</Year>
        <Month>05</Month>
        <Day>16</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>15</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">This study reviewed the former studies conducted on the usefulness of accuracy of focused assessment with
sonography for trauma (FAST) or any plain ultrasonography (US) scan in pediatric blunt abdominal trauma
(BAT), to assess its accuracy, sensitivity, specificity, and positive and negative predictive values (PPV and NPV).
Searches were conducted using the predefined keywords and Medical Subject Headings (MeSH) terms across
MEDLINE (PubMed), Scopus, Web of Science, Cochrane Collaboration Library, Embase, ClinicalTrials.gov, Magiran and SID.ir databases. Duplicate publications were excluded; then the titles and abstracts of eligible studies were reviewed for how they report blunt trauma, pediatric patients, and ultrasound modality in their text.&#xA0;Cochrane RevMan version 5.3 was used for the results analysis and assessing the risk of bias in the studies.
Out of 923 studies, 902 were excluded, and only 19 articles were included in this review, out of which one was
a randomized clinical trial (RCT), three were cohort studies, two were contrast-enhanced US (CEUS) studies,
and 13 were prospective or retrospective descriptive studies. The total population studied in the articles was
3454 patients. The results showed that the specificity of US in pediatric BAT was 93%, the sensitivity was 54%,
and the PPV in comparison to clinical examination was 73% versus 37%. CEUS protocol achieved 100% in both
sensitivity and specificity analysis. The only RCT study which included about 28% of the studies population also
reached a sensitivity and specificity of 97% and 98%, respectively using a combinational protocol of clinical examination, laboratory investigation, and US assessment.&#xA0;Ultrasonography does not provide more results than clinical examination, though better PPV results. A combination of follow-up, US examination, and laboratory requests may also have more accurate results. Moreover,&#xA0;a CEUS protocol may reach that goal with an acceptable time-saving outcome, but it needs more studies to be&#xA0;confirmed.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/751</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/751/372</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>6</Volume>
      <Issue>1</Issue>
      <PubDate PubStatus="epublish">
        <Year>2021</Year>
        <Month>07</Month>
        <Day>27</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">COVID-19 related hospitalizationous catheterization.&#xA0;Methods: The present case series and longitudinal study was conducted on patients with SVC syndrome in presence of central venous catheter who underwent venoplasty. Computed tomography (CT) venography was performed 1, 6 and 12 months after venoplasty. Facial swelling, facial discomfort, extremity edema, arteriovenous fistula (AVF) dysfunction, impairment in dialysis and SVC stenosis were measured at baseline and 1, 6 and 12 months after venoplasty.&#xA0;Results: Out of 20 investigated patients, 11 (55%) were male. Significantly decreases were observed in the median grades of facial swelling and extremity edema in the follow-up (P&lt;0.001). The decrease in facial discomfort was statistically insignificant (P=0.129), and the median grade of SVC stenosis significantly decreased from 1.5 to zero in the follow-up (P&lt;0.001). A statistically-significant decrease was observed in AVF dysfunction (P=0.007), and impairment in dialysis significantly decreased after the intervention during the follow-up (P&lt;0.001).&#xA0;Conclusion: Findings of the present study revealed the appropriate patency rate of endovascular treatment in patients with SVC syndrome in presence of central venous catheter.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/226</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/226/252</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>4</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2019</Year>
        <Month>12</Month>
        <Day>30</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">The Accuracy of GAP and MGAP Scoring Systems in Predicting Mortality in Trauma; a Diagnostic Accuracy Study</title>
    <FirstPage>e73</FirstPage>
    <LastPage>e73</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Mahnaz</FirstName>
        <LastName>Yadollahi</LastName>
        <affiliation locale="en_US">Trauma Research Center, Shahid Rajaee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Zahra</FirstName>
        <LastName>Ghaedsharaf</LastName>
        <affiliation locale="en_US">Trauma Research Center, Shahid Rajaee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Kazem</FirstName>
        <LastName>Jamali</LastName>
        <affiliation locale="en_US">Trauma Research Center, Shahid Rajaee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad Hadi</FirstName>
        <LastName>Niakan</LastName>
        <affiliation locale="en_US">Trauma Research Center, Shahid Rajaee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Forough</FirstName>
        <LastName>Pazhuheian</LastName>
        <affiliation locale="en_US">Trauma Research Center, Shahid Rajaee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mehrdad</FirstName>
        <LastName>Karajizadeh</LastName>
        <affiliation locale="en_US">Health Human Resources Research Center, School of Management &amp; Information Sciences, Shiraz University of Medical Sciences, Shiraz, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2019</Year>
        <Month>07</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2019</Year>
        <Month>11</Month>
        <Day>27</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Introduction: Trauma scoring systems help physicians and nurses to be informed of injuries to a patient and assist their decision making in the cases of trauma and importantly prediction of their outcome and prognosis.&#xA0;
Objective: This study aimed to compare the accuracy of GAP and MGAP scoring systems as predictors of mortality in trauma patients.&#xA0;
Methods: This diagnostic accuracy study was conducted amongst 1861 trauma patients admitted to Rajaee Hospital in Shiraz, Iran, during 2017. The data on demographic features were extracted from the patients&#x2019; records. Then, trauma scoring systems including injury severity score (ISS), GAP, MGAP, and Glasgow coma&#xA0;scale (GCS) were compared to evaluate their accuracy in predicting mortality. Area under the receiver operating characteristic (ROC) curve was used to evaluate the accuracy of different trauma scoring systems and detect the sensitivity and specificity in order to predict status of discharge after 24 hours.&#xA0;
Results: Based on the results, the area under the ROC curve was 0.8 for GCS. Moreover, Area Under Curve (AUC) of GAP was 0.91 and amongst different values, GAP value of &#x2264;18 was selected as the cut-off point, since it exhibited the best sensitivity and specificity (72.99 and 95.52, respectively). In addition, the area under the ROC curve was 0.9 for MGAP, and value of &#x2264;23 was selected as the cut-off point because it showed the best sensitivity and specificity (81.04 and 87.70, respectively). Additionally, AUC of ISS was 0.88.&#xA0;
Conclusion: Both GAP and MGAP methods were able to appropriately predict mortality and were not significantly different; hence, both can be used for the right triage of patients and to predict the severity of injuries and subsequent mortality. Moreover, GAP and ISS had the best specificity and sensitivity, respectively.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/230</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/230/255</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>4</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2020</Year>
        <Month>01</Month>
        <Day>07</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">The Role of C-reactive Protein in Diagnosis of Acute Complicated Appendicitis: A Diagnostic Accuracy Study</title>
    <FirstPage>e74</FirstPage>
    <LastPage>e74</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Neda</FirstName>
        <LastName>Karkeabadi</LastName>
        <affiliation locale="en_US">Department of General Surgery, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Seyed-Adel</FirstName>
        <LastName>Maleknia</LastName>
        <affiliation locale="en_US">Department of General Surgery, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Moein</FirstName>
        <LastName>Moghadam-Ahmadi</LastName>
        <affiliation locale="en_US">Department of General Surgery, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Sina</FirstName>
        <LastName>Salimi</LastName>
        <affiliation locale="en_US">Department of General Surgery, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Hossein</FirstName>
        <LastName>Torabi</LastName>
        <affiliation locale="en_US">Department of General Surgery, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Ehsan</FirstName>
        <LastName>Kazemnezhad-Leili</LastName>
        <affiliation locale="en_US">Department of Clinical Statistics, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad-Nima</FirstName>
        <LastName>Yadi</LastName>
        <affiliation locale="en_US">Department of Emergency Medicine, Poursina Medical &amp; Educational Center, Guilan University of Medical Sciences, Rasht, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2019</Year>
        <Month>07</Month>
        <Day>22</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2019</Year>
        <Month>12</Month>
        <Day>08</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Introduction: Acute appendicitis is one of the most common emergencies of general surgery. Contrary to simple appendicitis, the complicated cases are associated with higher morbidity and mortality. Except for pathology, no accurate diagnostic test has been found to identify complicated cases.&#xA0;
Objective: Here in, we aim to evaluate the serum C-Reactive Protein (CRP) level in both acute simple and complicated appendicitis.&#xA0;
Methods: In this diagnostic accuracy study, 199 patients with acute appendicitis were enrolled. The serum CRP level was evaluated in patients. Post-operatively, the patients were divided into simple and complicated appendicitis based on histopathological examination. Eventually, analysis of the CRP level and type of appendicitis was performed.&#xA0;
Results: Fifty-three patients were categorized into complicated appendicitis and 146 patients into simple appendicitis. The median of CRP was significantly higher in the complicated group. Additionally, the optimal cutoff point was as follows: [65.0 (25.0) vs 25.0 (51.0); P-value&lt; 0.001]. The optimal cutoff point for CRP was more than 42 with 81.1% sensitivity (95% CI: 68.0 to 90.6), and 67.8% specificity (95% CI: 59.6 to 75.3). The positive (PPV) and negative predictive values (NPV), based on the prevalence of complicated appendicitis (26.6%) for optimal cutoff point, were 47.8% (95% CI: 37.1 to 58.6) and 90.8% (95% CI: 83.8 to 95.5).&#xA0;
Conclusion: Our study revealed that evaluation of serum CRP levels could be useful and beneficial in the diagnosis of acute complicated appendicitis.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/223</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/223/256</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>4</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2020</Year>
        <Month>02</Month>
        <Day>17</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">MRI Findings in Children with the First Unprovoked Seizure Presenting to the Emergency Department; Does Developmental Delay Suggest the Importance of Brain MRI Evaluation?</title>
    <FirstPage>e75</FirstPage>
    <LastPage>e75</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Niloofar</FirstName>
        <LastName>Ayoobi-Yazdi</LastName>
        <affiliation locale="en_US">Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Science, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mehran</FirstName>
        <LastName>Beiraghi-Toosi</LastName>
        <affiliation locale="en_US">Department of Pediatric Neurology, Mashhad University of Medical Science, Mashhad, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Farzad</FirstName>
        <LastName>Ashrafi</LastName>
        <affiliation locale="en_US">Department of Neurology, Shohada Tajrish Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Atena</FirstName>
        <LastName>Aliabadi</LastName>
        <affiliation locale="en_US">Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Science, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mehran</FirstName>
        <LastName>Arab-Ahmadi</LastName>
        <affiliation locale="en_US">Advanced Diagnostic and Interventional Radiology Research Center, Tehran University of Medical Science, Tehran, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2019</Year>
        <Month>12</Month>
        <Day>29</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2020</Year>
        <Month>01</Month>
        <Day>19</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Introduction: The first unprovoked seizure (FUS) in children is a convulsive seizure with an unknown cause, which may be due to an underlying neurological disease or a manifestation of epilepsy.&#xA0;
Objective: The aim of this study was to evaluate the findings of brain magnetic resonance imaging (MRI) in pediatric patients with FUS, presenting to the emergency department (ED).&#xA0;
Methods: In this cross-sectional study, all children with FUS (age: &gt;1month and&lt;14 years), who were referred to the ED of Qaem Hospital, Mashhad, Iran from 2016 to 2019, were investigated. Medical records, brain MRI findings, electroencephalography (EEG) results, and developmental status of children were reviewed retrospectively.&#xA0;
Results: The brain MRI findings of 56 children with FUS were reviewed. The mean age of children was 3.92&#xB1;6.05 years, and the sex distribution was equal. Seventeen (30.4%) patients had abnormal EEG findings, while 13 (23.2%) patients&#x2019; had non-specific EEG findings. Neurological examination of 4 (7.1%) children was abnormal. Overall, 6 (10.7%) patients had non-specific abnormal brain MRI findings for seizure, while 3 (5.4%) patients had specific abnormal findings. A significant relationship was observed between the developmental status of children and abnormal MRI findings (P=0.04). However, MRI findings had no significant relationship with EEG or neurological findings (P&gt;0.05).&#xA0;
Conclusion: It may be useful to perform brain MRI for children with FUS presenting to ED, especially those who are suspected of developmental disorders.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/322</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/322/263</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>4</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2020</Year>
        <Month>02</Month>
        <Day>17</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Predictors of In-hospital Mortality after Primary Percutaneous Coronary Intervention for ST-segment Elevation Myocardial Infarction</title>
    <FirstPage>e76</FirstPage>
    <LastPage>e76</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Soraya</FirstName>
        <LastName>Siabani</LastName>
        <affiliation locale="en_US">University of Technology Sydney, Sydney, NSW, Australia</affiliation>
      </Author>
      <Author>
        <FirstName>Maryam</FirstName>
        <LastName>Babakhani</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Nahid</FirstName>
        <LastName>Salehi</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad</FirstName>
        <LastName>Rouzbahani</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Javad</FirstName>
        <LastName>Azimivaghar</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Sousan</FirstName>
        <LastName>Mahmoudi</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Yousef</FirstName>
        <LastName>Rahmani</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Hossein</FirstName>
        <LastName>Siabani</LastName>
        <affiliation locale="en_US">Cardiovascular Research Centre, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2020</Year>
        <Month>01</Month>
        <Day>06</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2020</Year>
        <Month>02</Month>
        <Day>08</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Introduction: Treatment of myocardial infarction (MI) has been successfully developed, especially after introducing primary percutaneous coronary intervention (PPCI) as it nowadays is the recommended treatment for ST-segment elevation myocardial infarction (STEMI).&#xA0;
Objective: This study aimed to evaluate the in-hospital mortality of STEMI patients treated with PPCI according to gender and other likely risk factors.&#xA0;
Methods: This cross-sectional study presents a part of the results of a single-center registry in Imam Ali cardiovascular center affiliated to Kermanshah University of medical science (KUMS). From June 2016 to December 2017, 731 consecutive patients undergoing PPCI registered. Data were collected using a case report form developed by European Observational Registry Program (EORP). The relationship between in-hospital mortality and predicting variables was assessed using the Chi-square test, t-test, and univariate and multivariate logistic regression models (Forward LR).&#xA0;
Results: Totally, 155 patients (approximately 21%) were female. The mean age of women and men was 65.2 and 57.5, respectively (p=0.001). There were differences between women and men in hypertension (58.1% vs. 30.4%, respectively, p=0.001), diabetes mellitus (26.5% vs. 14.9%; p=0.001), hypercholesterolemia (37.4% vs. 18.6%; p=0.001), and history of prior congestive heart failure (5.2% vs. 2.0%; p=0.016). Although more men were current smokers (58.7% (men) vs. 15.5% (women); p=0.001). Women had a significantly greater incidence of multi-vessel disease, thrombolysis in myocardial infarction (TIMI) flow grade of 0/1 before PPCI, and longer symptom-to-balloon time. In-hospital mortality was higher in women than in men (5.2% vs. 1.9%; p=0.024). Multivariate analysis identified age &#x2265; 60 years, Killip class&#x2265; II, and post-procedural TIMI flow grade &lt; 3, but not female sex, as independent predictors of in-hospital mortality.&#xA0;
Conclusion: In-hospital mortality after PPCI in women was higher than men, though this difference was likely due to the severe clinical profile in women. Also, female gender was not identified as an independent predictor of death.</abstract>
    <web_url>https://fem.tums.ac.ir/index.php/fem/article/view/327</web_url>
    <pdf_url>https://fem.tums.ac.ir/index.php/fem/article/download/327/264</pdf_url>
  </Article>
  <Article>
    <Journal>
      <PublisherName>Tehran University of Medical Sciences</PublisherName>
      <JournalTitle>Frontiers in Emergency Medicine</JournalTitle>
      <Issn>2717-3593</Issn>
      <Volume>4</Volume>
      <Issue>3</Issue>
      <PubDate PubStatus="epublish">
        <Year>2020</Year>
        <Month>05</Month>
        <Day>05</Day>
      </PubDate>
    </Journal>
    <title locale="en_US">Professional Resilience among Trauma Emergency Department Nurses in Iran: A Qualitative Study</title>
    <FirstPage>e77</FirstPage>
    <LastPage>e77</LastPage>
    <AuthorList>
      <Author>
        <FirstName>Roohangiz</FirstName>
        <LastName>Norouzinia</LastName>
        <affiliation locale="en_US">Health Management and Economics Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Mohammad Hosein</FirstName>
        <LastName>Yarmohammadian</LastName>
        <affiliation locale="en_US">Health Management and Economics Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Masoud</FirstName>
        <LastName>Ferdosi</LastName>
        <affiliation locale="en_US">Health Management and Economics Research Centre, Isfahan University of Medical Sciences, Isfahan, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Gholamreza</FirstName>
        <LastName>Masoumi</LastName>
        <affiliation locale="en_US">Emergency Management Research Center, Iran University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
      <Author>
        <FirstName>Abbas</FirstName>
        <LastName>Ebadi</LastName>
        <affiliation locale="en_US">Behavioural Sciences Research Centre, Life style institute, Baqiyatallah University of Medical Sciences, Tehran, Iran</affiliation>
      </Author>
    </AuthorList>
    <History>
      <PubDate PubStatus="received">
        <Year>2020</Year>
        <Month>03</Month>
        <Day>25</Day>
      </PubDate>
      <PubDate PubStatus="accepted">
        <Year>2020</Year>
        <Month>05</Month>
        <Day>03</Day>
      </PubDate>
    </History>
    <abstract locale="en_US">Introduction: Nursing staff&#x2019;s professional resilience plays an important role in overcoming the stressful and adverse situations common to the trauma emergency department and helps to achieve positive outcomes.&#xA0;
Objective: This study intended to explore the concept of resiliency among Iranian trauma emergency department nurses.&#xA0;
Methods: Data were collected using semi-structured interviews with 21 trauma emergency department nurses and analysed through a deductive content analysis based on the general conceptual model of resilience derived from King and Rothstein&#x2019;s study.&#xA0;
Results: All codes were nested into the four main categories of the above-mentioned model including: 1) Personal characteristics; 2) Opportunities, supports and resources; 3) Self-regulatory processes; 4) Positive outcomes. Some new sub-categories including Professional abilities (sub-category of Personal characteristics) and Cooperation with colleagues and Volunteers&#x2019; declaration of readiness (sub-categories of opportunities, supports and reso