Tehran University of Medical Sciences Frontiers in Emergency Medicine 2717-3593 6 3 2022 02 27 e40 e40 EN Victoria Chegini Pediatric Intensive Care, Department of Pediatrics, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Fatemeh Omidi Department of Cardiology, School of Medicine, Imam Hossein Hospital, Shahid Behehsti University of Medical Sciences, Tehran, Iran Fatemeh Shojaeian Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland, US Hamidreza Hatamabadi Department of Emergency and Critical Care Medicine, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Mina Farshidgohar Department of Pediatrics, School of Medicine, Qods Teaching Hospital, Qazvin University of Medical Sciences, Qazvin, Iran 2022 02 08 2022 02 22 Since the emergence of COVID-19 in late December 2019, patients were presented at the hospitals with different symptoms, including cardiac manifestations. Recent records of coronavirus infection in children and adolescents have been accompanied by multisystem inflammatory syndrome (MIS-C). Here, we describe a 6 -year-old girl with no history of cardiac disease, infected with COVID-19 and presented at the emergency department with fever and cardiac manifestations. Her echocardiography findings favored myocarditis with restrictive (severe) diastolic dysfunction, a rare manifestation of COVID-19 among children. Unfortunately, despite standard treatment of myocarditis and supportive care, the patient passed away. Therefore, it seems necessary to develop a guideline for the recent cardiac consequences of the pandemic among children and follow their presentations carefully. https://fem.tums.ac.ir/index.php/fem/article/view/957 https://fem.tums.ac.ir/index.php/fem/article/download/957/394