Tehran University of Medical Sciences Frontiers in Emergency Medicine 2717-3593 9 1 2025 02 05 e9 e9 EN Khazar Garjani Department of Emergency Medicine, Sina hospital, Tehran University of Medical Sciences, Tehran, Iran. Sepideh Aarabi Department of Emergency Medicine, Sina hospital, Tehran University of Medical Sciences, Tehran, Iran. 2024 12 11 2025 01 18 Pyogenic liver abscess (PLA) is a rare but serious condition that can be life-threatening. Recent developments in diagnostic techniques and treatment have resulted in earlier detection and intervention and hence reduction in mortality rates. Despite these improvements, PLA remains a clinical challenge due to its hidden symptoms and associated health risks. PLA may be caused by seeding from appendicitis. We present a 52-year-old woman presented with PLA due to appendicitis. Upon physical examination, laboratory study and imaging, an acute appendicitis with pyogenic liver abscess were found. The patient underwent percutaneous drainage of the abscesses with a catheter and an interval appendectomy. https://fem.tums.ac.ir/index.php/fem/article/view/1523 https://fem.tums.ac.ir/index.php/fem/article/download/1523/511