Tehran University of Medical Sciences Frontiers in Emergency Medicine 2717-3593 6 4 2022 08 09 e54 e54 Kenzie David Kao Saba University School of Medicine, Saba, Dutch Caribbean, Netherlands Saad Ahmed SUNY Downstate College of Medicine, NY, USA Reshma Pyala Medical University of Lublin, Lublin, Poland Mohammed Alsabri Department of Emergency Medicine, Al-Thawra Modern General Teaching Hospital, Sana’a City, Yemen 2022 07 10 2022 08 09 Since the authoring of the seminal report by the Institute of Medicine (IOM) “To Err is Human: Building a Safer Health System” in 2000, there has been an increased focus on patient safety and the responsibility born by the healthcare system to reduce what are known as adverse events (AE). One of the recommendations of the IOM report was the establishment and development of Incident Reporting System (IRS) that would track AE resulting in serious injury and death. The Joint Commission in the USA similarly requires all hospitals have and use an IRS. The objective of this review is to explore barriers and feature of IRS and patient safety.      https://fem.tums.ac.ir/index.php/fem/article/view/1043 https://fem.tums.ac.ir/index.php/fem/article/download/1043/419